WP4: Exercise, Bicarbonate & CKD
A 2x2 factorial trial will address the following questions:
- Can resistance training overcome the negative effects of acidosis and elicit an increase in muscle mass in pre-dialysis CKD patients?
- Does the addition of acidosis correction with bicarbonate supplementation maximise this anabolic effect?
- Can the resultant gain in muscle mass increase physical functioning, habitual daily activity and quality of life?
Theme 2 Work Packages
Tightly controlled acute and chronic experimental training studies will be used to address the... Read more
Cohort development and an experimental randomised controlled trial will address the following... Read more
Laboratorybased experimental investigations and multidisciplinary device development teams will... Read more