WP4: Exercise, Bicarbonate & CKD


      A 2x2 factorial trial will address the following questions: weights


      1. Can resistance training overcome the negative effects of acidosis and elicit an increase in muscle mass in pre-dialysis CKD patients?
      2. Does the addition of acidosis correction with bicarbonate supplementation maximise this anabolic effect?
      3. Can the resultant gain in muscle mass increase physical functioning, habitual daily activity and quality of life?

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          Theme 2 Work Packages

          Theme 2 WP1

          Tightly controlled acute and chronic experimental training studies will be used to address the... Read more

          Theme 2 WP2

          Cohort development and an experimental randomised controlled trial will address the following... Read more

          Theme 2 WP3

          Laboratorybased experimental investigations and multidisciplinary device development teams will... Read more

          Theme 2 WP5

          Placebo controlled experimental trials will address the following questions Can Vitamin D... Read more