Friday 11, July 2014

      Melanie J Davies – Professor of Diabetes Medicine


      Diabetes Research Centre, College of Medicine, Biological Sciences and Psychology, University of Leicester, Director of NIHR Biomedical
      Research Unit (BRU) in Diet, Lifestyle & Nutrition, Affiliated to the Department of Health Sciences.


       Professor Melanie Davies

      Research Interests:

       

      • Lifestyle and physical activity interventions in the treatment of chronic disease
      • Clinical Trial Design
      • Complex interventions including self-management and diabetes prevention
      • Novel glucose lowering therapies
      • Sedentary behaviour and health
      • Novel therapies for obesity
      • Type 2 diabetes mellitus in younger patients
      • Diabetes Prevention

       

       

      Selected Current Research Projects:

       

      • Effect of sedentary behaviour on long term health
      • Efficacy and outcome trials with new classes of glucose lowering therapy including incretin based therapy and SGLT-2 inhibitors
      • Study of incretin based therapies on cardiac dysfunction in young type 2 patients
      • Effect of exercise on appetite in type 2 diabetes mellitus
      • Development of group based lifestyle interventions in different clinical groups with chronic disease

       

       

      Professional Activities:

       

      • Honorary Consultant Physician
      • National Institute for Health Research (NIHR) Senior Investigator, awarded 2012 for 5 years after which she will become an emeritus Senior Investigator
      • Director of NIHR Biomedical Research Unit (BRU) in Diet, Lifestyle & Nutrition
      • Director of Leicester Clinical Trials Unit (CTU)
      • CRN East Midlands Lead for Division 2 (Diabetes, Stroke, Cardiovascular Disease, Metabolic & Endocrine Disorders and Renal Disorders)


      Contact:

       

      Leicester Diabetes Centre

      Leicester General Hospital

      Gwendolen Road

      Leicester LE5 4PW

       


      PUBLICATIONS

      A Selection of Recent Peer Reviewed Publications:

       

      1. Brady EM, Davies MJ, Gray LJ, Saeed MA, Smith D, Hanif W, Khunti K. A randomized controlled trial comparing the GLP-1 receptor agonist Liraglutide to a sulphonylurea as add on to Metformin in patients with established type 2 diabetes during Ramadan: the Treat for Ramadan Trial. Diabetes Obes Metab. 2014 Jun;16(6):527-36. doi: 10.1111/dom.12249. Epub 2014 Jan 26. PMID:24373063
      1. Khunti K, Wolden M, Thorsted BL, Andersen M, Davies MJ. Response to Esposito et al. Comment on Khunti et al. Clinical inertia in people with type 2 diabetes: a retrospective cohort study of more than 80,000people. Diabetes Care May 2014 37:5 e114; doi:10.2337/dc14-0165. PMID 24757241
      1. Barnard KD, Lloyd CE, Dyson PA, Davies MJ, O’Neill S, Kanumilli N, Lawton J, Ziegler R, Holt RIG. Kaleidoscope model of diabetes care: time for a rethink?. Diabetic Medicine, 2014 May;31(5):522-30.doi:10.1111/dme.12400. PMID 24506524
      1. Black JA, Sharp SJ, Wareham NJ, Sandbaek A, Rutten GEHM, Lauritzen T, Khunti K, Davies MJ, Borch-Johnsen K, Griffin SJ, Simmons RK. Does early intensive multifactorial therapy reduce modelled cardiovascular risk in individuals with screen-detected diabetes? Results from the ADDITION-Europe cluster randomized trial. Diabetic Medicine 31(6):647-656 Jun 2014, doi:10.1111/dme.12410. PMID 24533664
      1. Huffman K, Sun J, Thomas L, Bales C, Califf R, Yates T, Davies MJ, Holman R, McMurray J, Bethel MA, Tuomilehto J, Haffner S, Kraus W. Impact of baseline physical activity and diet behaviour on metabolic syndrome in a pharmaceutical trial: Results from NAVIGATOR. Metabolism January 2014, doi:10.1016/j.metabol.2014.01.002. PMID 24559843
      1. Parekh S, Bodicoat DH, Brady E, Webb D, Mani H, Mostafa S, Levy MJ, Khunti K, Davies MJ. Clinical characteristics of people experiencing biochemical hypoglycaemia during an oral glucose tolerance test: Cross-sectional analyses from a UK multi-ethnic population. Diabetes Res Clin Pract. 2014 Jun;104(3):427-34 DOI: 10.1016/j.diabres.2014.02.013 PMID 24685116
      1. Khunti K, Vora J, Davies MJ. Results from the UK cohort of SOLVE: Providing insights into the timing of insulin initiation in people with poorly-controlled type 2 diabetes in routine clinical practice. Primary Care Diabetes 2014 Apr;8(1):57-63. doi: 10.1016/j.pcd.2013.11.010. Epub 2013 Dec 27. PMID 24378771
      1. Sandbæk A, Griffin SJ, Sharp S, Simmons R, Borch-Johnsen K, Rutten G, Donk M, Wareham NJ, Lauritzen T, Davies MJ, Khunti K. Effect of early multifactorial therapy compared to routine care on microvascular outcomes at 5 years in people with screen-detected diabetes. A Randomised Controlled Trial: the ADDITION-Europe study. Diabetes Care 37(7):2015-2023 Jul 2014. PMID 24784827
      1. Stone M, Aujla N, Taub N, Davies MJ, Khunti K. Identifying people with or at risk of type 2 diabetes. Prim Care Cardiovasc J doi:10.3132/pccj.2014.013.
      2. Wilmot EG, Leggate M, Khan JN, Yates T, Gorely T, Bodicoat DH, Khunti K, Kuijer JPA, Gray LJ, Singh A, Clarysse P, Croisille P, Nimmo MA, McCann GP, Davies MJ. Type 2 diabetes mellitus and obesity in young adults: the extreme phenotype with early cardiovascular dysfunction. Diabetic Medicine, 2014 Jul;31(7):794-8. doi: 10.1111/dme.12431. Epub 2014 Apr 2.PMID 24606573
      3. Gray L, Khunti K, Wilmot E, Yates T, Davies MJ. External validation of two diabetes risk scores in a young UK South Asian population. Diabetes Research and Clinical Practice, 104(3):451-458 Jun 2014, dx.doi.org/doi:10.1016/j.diabres.2014.03.018. PMID 24785738
      4. Barber SR, Davies MJ, Khunti K, Gray LJ. Risk assessment tools for detecting those with pre-diabetes: A systematic review. Diabetes Research and Clinical Practice, 105(1):1-13 Jul 2014 dx.doi.org/10.1016/j.diabres.2014.03.007. PMID 24694663
      5. Dunkley AJ, Bodicoat DH, Greaves C, Russell C, Yates T, Davies MJ, Khunti K. Diabetes Prevention in the Real World: Effectiveness of Pragmatic Lifestyle Interventions for the Prevention of Type 2 Diabetes and of the Impact of Adherence to Guideline Recommendations. A Systematic Review and Meta-analysis. Diabetes Care. 2014 Apr;37(4):922-33 DOI: 10.2337/dc13-2195 PMID 24652723
      6. Black JA, Sharp SJ, Wareham NJ, Sandbæk A, Rutten GE, Lauritzen T, Khunti K, Davies MJ, Borch-Johnsen K, Griffin SJ, Simmons RK. Change in cardiovascular risk factors following early diagnosis of type 2 diabetes: a cohort analysis of a cluster-randomised trial, Br J Gen Pract. 2014 Apr;64(621):e208-16 doi: 10.3399/bjgp14X677833 PMID 24686885
      7. Davies MJ, Gross JL, Ono Y, Sasaki T, Bantwal G, Gall M, Niemeyer, Seino H. Efficacy and safety of insulin degludec given as part of basal−bolus treatment with mealtime insulin aspart in type 1 diabetes: a 26-week randomised, open-label, treat-to-target non-inferiority trial. Diabetes, Obesity and Metabolism 2014 Apr 7. doi: 10.1111/dom.12298 PMID:24702700
      8. Kuznetsov L, Griffin S, Davies MJ, Lauritzen T, Khunti K, Rutten G, Simmons R. Diabetes-specific quality of life but not health status is independently associated with glycaemic control among patients with type 2 diabetes: A cross-sectional analysis of the ADDITION-Europe trial cohort. Diabetes Research and Clinical Practice, 2014 May;104(2):281-7. doi: 10.1016/j.diabres.2013.12.029. Epub 2014 Jan 15. PMID 24636627
      9. Carey M, Mandalia P, Daly H, Gray LJ, Hale R, Martin Stacey L, Taub N, Skinner T, Stone M, Heller S, Khunti K, Davies MJ. Increasing capacity to deliver diabetes self-management education: results of the DESMOND lay educator equivalence trial. Diabetic Medicine April 2014, doi: 10.1111/dme.12483. PMID 24798205Skinner T, Khunti K, Carey ME, Dallosso H, Heller S, Davies MJ. Stability and predictive utility over 3 years of illness beliefs of individuals recently diagnosed with type 2 diabetes mellitus. Diabetic Medicine, April 2014, doi: 10.1111/dme.12484. PMID 24798395
      10. Yates T, Davies MJ, Edwardson C, Bodicoat D, Biddle S, Khunti K. Adverse Responses and Physical Activity: Secondary Analysis of the PREPARE Trial. Med Sci Sports Exerc. 2014 Feb 4. [Epub ahead of print]. PMID:24500536Bodicoat D, Gray LJ, Henson J, Webb D, Guru A, Misra A, Gupta R, Vikram N, Sattar N, Davies MJ, Khunti K. Body mass index and waist circumference cut-points in multi-ethnic populations from the UK and India: the ADDITION-Leicester, Jaipur heart watch and New Delhi cross-sectional studies. PLoS One. 2014 Mar 5;9(3):e90813. doi: 10.1371/journal.pone.0090813. PMID:24599391
      11. Willis A, Rivers P, Gray LJ, Davies MJ, Khunti K. The Effectiveness of Screening for Diabetes and Cardiovascular Disease Risk Factors in a Community Pharmacy Setting. PLoS One. 2014 Apr 1;9(4):e91157. doi: 10.1371/journal.pone.0091157. PMID:24690919Seidu S, Davies MJ, Mostafa S, deLusignan S, Khunti K. Prevalence and characteristics in coding, classification and diagnosis of diabetes in primary care. Postgraduate Medical Journal 90(1059):13-17 01 Jan 2014. PMID:24225940
      12. Gilani A, Davies MJ, Khunti K. Religious Fasting and Hypoglycaemia in people with Diabetes. Diabetic Hypoglycemia June 2014, Volume 7, Issue 1: page 15-19.
      13. Khan J, Wilmot E, Leggate M, Singh A, Yates T, Nimmo M, Khunti K, Horsfield M, Plein S, Biglands J, Clarysse P, Croisille P, Davies MJ, McCann G. Subclinical diastolic dysfunction in young adults with Type 2 diabetes mellitus: a multiparametric contrast-enhanced cardiovascular magnetic resonance pilot study assessing potential mechanisms. Eur Heart J Cardiovasc Imaging. 2014 Jun 26. pii: jeu121. [Epub ahead of print]. PMID:24970723

       

       

      2013

       

      1. Carter P, Gray L, Talbot D, Morris DH, Khunti K, Davies MJ. Fruit and vegetable intake and the association with glucose parameters: a cross-sectional analysis of the Let’s Prevent Diabetes Study. European Journal of Clinical Nutrition 2013; 67: 12-17, doi:10.1038/ejcn.2012.174. PMID 2329978
      1. Henson J, Yates T, Biddle SJH, Edwardson C, Khunti K, Wilmot E, Gray LJ, Gorely T, Nimmo M, Davies MJ. Associations of objectively measured sedentary behaviour and physical activity with markers of cardio-metabolic health in a primary care, high risk population. Diabetologia. 2013 May;56(5):1012-20, doi:10.1007/s00125-013-2845-9. PMID 23456209
      1. Thomasouli MA, Brady E, Davies MJ, Hall A, Khunti K, Gray LJ. The impact of diet and lifestyle management strategies for obstructive sleep apnoea in adults: a systematic review and meta-analysis of randomised controlled trials. Sleep Breath. 2013 Sep;17(3):925-35, doi:10.1007/s11325-013-0806-7. PMID 23361137
      1. Mostafa S, Khunti K, Kilpatrick ES, Webb D, Srinivasan BT, Gray LJ, Davies MJ. Diagnostic performance of using one- or two-HbA1c cut-point strategies to detect undiagnosed type 2 diabetes and impaired glucose regulation within a multi-ethnic population. Diab Vasc Dis Res. 2013 Jan;10(1):84-92, doi:10.1177/1479164112451473. PMID 22773521
      1. Gray LJ, Barros H, Raposo L, Khunti K, Davies MJ, Santos AC. The development and validation of the Portuguese risk score for detecting type 2 diabetes and impaired fasting glucose.Prim Care Diabetes. 2013 Apr;7(1):11-18, doi:10.1016/j.pcd.2013.01.003. PMID 23357741
      1. Khunti K, Davies MJ. Diabetes prevention: NICE opportunity for implementing programmes in the real-world setting. Diabet Med. 2013 Jan;30(1):1-2, doi:10.1111/dme.12042. PMID 23072427
      1. Davies MJ, Gagliardino JJ, Gray LJ, Khunti K, Mohan V, Hughes R. Real-world factors affecting adherence to insulin therapy in patients with Type 1 or Type 2 diabetes mellitus: a systematic review.Diabet Med. 2013 May;30(5):512-24, doi:10.1111/dme.12128. PMID 23323988
      1. Wilmot EG, Edwardson CL, Achana FA, Davies MJ, et al. Erratum to: Sedentary time in adults and the association with diabetes, cardiovascular disease and death: systematic review and meta-analysis. Diabetologia 56(4):942-943, doi:10.1007/s00125-013-2842-z. Apr 2013 PMID 23370529
      1. Khunti K, Morris DH, Weston CL, Gray LJ, Webb DR, Davies MJ. Joint prevalence of diabetes, impaired glucose regulation, cardiovascular disease risk and chronic kidney disease in South Asians and white Europeans. PLoS One. 2013;8(1):e55580, doi:10.1371/journal.pone.0055580. PMID: 23383233.
      2. Khunti K, Fisher H, Paul S, Iqbal M, Davies MJ, Siriwardena AN. Severe hypoglycaemia requiring emergency medical assistance by ambulance services in the East Midlands: A retrospective study. Prim Care Diabetes. 2013 Jul;7(2):159-65, doi:10.1016/j.pcd.2013.01.001. PMID: 23375384
      3. Yates T, Henson J, Khunti K, Morris DH, Edwardson C, Brady E, Davies MJ. Effect of physical activity measurement type on the association between walking activity and glucose regulation in a high-risk population recruited from primary care. Int J Epidemiol. 2013 Apr;42(2):533-40, doi:10.1093/ije/dyt015. PMID 23421988
      4. McDonough C, Dunkley AJ, Aujla N, Davies MJ, Khunti K. The association between body mass index and health related quality of life: influence of ethnicity on this relationship. Diabetes, Obesity and Metabolism 15(4):342-348, doi:10.1111/dom.12033, April 2013 PMID 23137289
      5. Wilmot E, Edwardson C, Biddle SJH, Gorely T, Henson J, Khunti K, Nimmo M, Yates T, Davies MJ. Prevalence of diabetes and impaired glucose tolerance in younger UK adults: Insights from Project STAND baseline data. Diabet Med. 2013 Jun;30(6):671-675, doi:10.1111/dme.12173. PMID 23506383
      6. Hunt BD, Hiles S, Chauhan A, Ighofose C, Bharakhada N, Jain A, Davies MJ, Khunti K. Evaluation of the Healthy LifeCheck programme: A vascular risk assessment service for community pharmacies in Leicester City, UK. J Public Health (Oxf). 35(3):440-446, doi:10.1093/pubmed/fdt017. Sep 2013 PMID 23479477
      7. Khunti K, Weston C, Gholap N, Molokhia M, Paul S, Millett C, Curcin V, Majeed A, Davies MJ. All cause mortality in relation to glycated haemoglobin in individuals with newly diagnosed type 2 diabetes: a retrospective cohort study. British Journal of Diabetes and Vascular Disease 13(1):22-30, doi:10.1177/1474651412468297. Jan 2013.
      8. Khagram L, Martin CR, Davies MJ, Speight J. Psychometric validation of the Self-Care Inventory-Revised (SCI-R) in UK adults with type 2 diabetes using data from the AT.LANTUS Follow-on study. Health Qual Life Outcomes. 2013 Feb 26;11:24, doi:10.1186/1477-7525-11-24. PMID 23443007
      9. Mani H, Levy MJ, Davies MJ, Morris DH, Gray LJ, Bankart J, Blackledge H, Khunti K, Howlett TA. Diabetes and cardiovascular events in women with polycystic ovary syndrome: a 20-year retrospective cohort study. Clin Endocrinol (Oxf). 2013 Jun;78(6):926-34, doi:10.1111/cen.12068. PMID 23046078
      10. Morris DH, Khunti K, Achana F, Srinivasan B, Gray LJ, Davies MJ, Webb D. Progression rates from HbA1c 6.0-6.4% and other prediabetes definitions to type 2 diabetes: a meta-analysis. Diabetologia. 2013 Jul;56(7):1489-93, doi:10.1007/s00125-013-2902-4. PMID 23584433
      11. Makda SI, Davies MJ, Wilmot E, Bankart J, Yates T, Varghese EM, Fisher H, Anwar A, Khunti K. Prescribing in pregnancy for women with diabetes: use of potential teratogenic drugs and contraception. Diabet Med. 2013 Apr;30(4):457-463, doi:10.1111/dme.12051. PMID 23110381The ORIGIN Trial Investigators. Characteristics Associated With Maintenance of Mean A1C 6.5% in People With Dysglycemia in the ORIGIN Trial Diabetes Care 2013 May 8 [Epub ahead of print] PMID 23656980 Need full citation
      12. Bales C, Haffner S, Thomas L, Sun J, Yates T, Huffman K, Califf R, Toumilehto J, McMurray J, Holman R, Davies M, Kraus W. Diet and other health-related behaviours of individuals with impaired glucose tolerance, cardiovascular disease (CVD) or CVD risk: A global view from the NAVIGATOR study. FASEB Journal. April 9, 2013 27:1055.5
      13. Khunti K, Davies MJ, Kalra S. Self-titration of insulin in the management of people with type 2 diabetes: A practical solution to improve management in primary care. Diabetes, Obesity and Metabolism Aug 2013; 15(8);690-700. doi:10.1111/dom.12053. PMID 23253563
      14. Gray LJ, Leigh T, Davies MJ, Patel N, Stone M, Bonar M, Khunti K. Systematic review of the development, implementation and availability of smart-phone applications for assessing Type 2 diabetes risk. Diabetic Medicine, 30(6):758-760, June 2013. doi:10.1111/dme.12115. PMID 23683104
      15. Khunti K, Wolden M, Thorsted BL, Andersen M, Davies MJ. Clinical inertia in patients with type 2 diabetes: a retrospective cohort study of over 80,000 people Diabetes Care, 36(11), 3411-3417. doi:10.2337/dc13-0331. 2013 Jul 22. [Epub ahead of print]. PMID 23877982
      16. Munro N, Holt RIG, Davies MJ, Forbes A. DAWN2 study findings: psychosocial support and structured education need to be more widespread. Practical Diabetes, 30(6), 239-240 Jul 2013. doi:10.1002/pdi.1784.
      17. Webb DR, Herbert K, Davies MJ, Khunti K, Sattar N, Stehouwer CDA. Biomarker Research in Glucose Disorders: Current Concepts and Clinical Applications Journal of Diabetes Research, 2013:290671. doi: 10.1155/2013/290671. Epub 2013 Jun 17 PMID 23844372
      18. Carter P, Troughton J, Khunti K, Davies MJ, Achana F, Gray LJ. Mediterranean diet improves HbA1c but not fasting blood glucose as compared to alternative dietary strategies: A network meta-analysis. . J Hum Nutr Diet. 27, 280–297 doi:10.1111/jhn.12138. [First published online 22 Jun 13]. PMID 23790149
      19. Davies M, Heller S, Sreenan S, Sapin H, Adetunji O, Tahbaz A, Vora J. Once-Weekly Exenatide Versus Once- or Twice-Daily Insulin Detemir: Randomized, open-label, clinical trial of efficacy and safety in patients with type 2 diabetes treated with metformin alone or in combination with sulfonylureas.Diabetes Care. 2013 May;36(5):1368-76, doi:10.2337/dc12-1333. PMID 23275363
      20. Webb D, Khunti K, Chatterjee S, Jarvis J, Davies MJ. Adipocytokine associations with insulin resistance in British South Asians. Journal Diabetes Research, 2013;561016. doi: 10.1155/2013/561016. Epub 2013 Feb 25. PMID 23671875
      21. Gholap N, Davies MJ, Mostafa S, Khunti K. Diagnosing type 2 diabetes and identifying high-risk individuals using the new glycated haemoglobin (HbA1c) criteria. Br J Gen Pract 2013 Feb;63(607):e165-7, doi:10.3399/bjgp13X663244. PMID 23561696
      22. Carter P, Gray L, Morris D, Davies MJ, Khunti K. South Asian individuals at high risk of type 2 diabetes have lower plasma vitamin C levels than White Europeans. Journal of Nutritional Science, 2013:2;e21:1 – 5
      23. Gough SC, Harris S, Woo V, Davies M. Insulin degludec: overview of a novel ultra long-acting basal insulin.Diabetes Obes Metab. 2013 Apr;15(4):301-9, doi:10.1111/dom/12052. PMID 23240573
      24. Peyrot M, Burns KK, Davies M, Forbes A, Hermanns N, Holt R, Kaira S, Nicolucci A, Pouwer F, Wens J, et al. Diabetes attitudes wishes and needs 2 (DAWN 2): A multinational, multi-stakeholder study of psychosocial issues in diabetes and person-centred diabetes care. Diabetes Res Clin Pract. 2013 Feb;99(2):174-84. doi:10.1016/j.diabres.2012.11.016. PMID 23273515
      25. Chilton M, Dunkley A, Carter P, Davies MJ, Khunti K, Gray LJ. The effect of anti-obesity drugs on waist circumference: a mixed treatment comparison. Diabetes, Obesity and Metabolism, 2013 Aug 21. doi:10.1111/dom.12198. PMID 23964810
      26. Stone MA, Patel N, Amin S, Daly H, Carey M, Khunti K, Davies MJ, Dogra N. Developing and initially evaluating two training modules for healthcare providers, designed to enhance cultural diversity awareness and cultural competence in diabetes. Diversity and Equality in Health and Care; 10(3):177-184 Aug 2013.
      27. Yates TE, Haffner S, Schulte P, Thomas L, Huffman K, Bales C, Califf R, Holman R, McMurray J, Bethel A, Davies MJ, et al. The association between change in daily ambulatory activity and cardiovascular events in those with impaired glucose tolerance: Cohort analysis of the NAVIGATOR trial. Lancet. 2014 Mar 22;383(9922):1059-66. Epub 2013 Dec 20. doi: 10.1016/S0140-6736(13)62061-9 PMID: 24361242
      28. Aujla N, Stone MA, Taub N, Davies MJ, Khunti K. Identifying people with type 2 diabetes and those at risk:Lessons from the measure your waist (MY WAIST) mixed-methods study in UK primary care. Primary Care Diabetes2013 Dec;7(4):261-7. doi:10.1016/j.pcd.2013.085.002. PMID 24021479
      29. Khunti K, Willis A, Davies M, Khunti K. The role of Pharmacists in the management of type 2 diabetes: a literature review. Diabetes and Primary Care 15 (3):131-140 2013.
      30. Wilmot EG, Leggate M, Khan JN, Yates T, Gorely T, Morris DH, Khunti K, Pa Kuijer J, Gray LJ, Singh A, Davies MJ, et al. Type 2 diabetes and obesity in young adults: The Extreme phenotype with early cardiovascular dysfunction. Diabetologia 2013. Need full citation
      31. Seidu S, Khunti K, Davies M.J. Diabetes Screening and the NHS Health Check programme: Can we begin to address ethnic disparities?. Diabetes and Primary Care 15(5), 234-237. 2013
      32. Henson J, Yates T, Edwardson C L, Khunti K, Talbot D, Gray LJ, Davies MJ. Sedentary time and markers of chronic low-grade inflammation in a high risk population. PLoS One, 8(10), e78350. doi:10.1371/journal.pone.0078350. 2013. PMID 24205208
      33. Van den Donk M, Griffin SJ, Stellato SK, Simmons RK, Sandbaek A, Laurtizen T, Khunti K, Davies MJ, Borch-Johnsen K, Wareham NJ, Rutten GEHM. Effect of early intensive multifactorial therapy compared with routine care on self-reported health status, general well-being, diabetes-specific quality of life and treatment satisfaction in screen-detected type 2 diabetes mellitus patients (ADDITION-Europe): a cluster-randomised trial. Diabetologia, 56(11), 2367-2377. doi:10.1007/s00125-013-3011-0. 2013. PMID 23959571
      34. Mani H, Khunti K, Levy M, Davies MJ. Diabetes advice for women with polycystic ovary syndrome; Prevention, Prevention, Prevention. Diabetes Management, 2013, 3(6), 1-14. doi: 10.2217/dmt.13.54

       

      A Selection of Current Grants Held:

       

      • 2011-2016 – NIHR Programme Grant “Development of a structured screening and lifestyle intervention for prevention of Type 2 Diabetes Mellitus in a population with Learning Disabilities” (£1,894,000)

       

      • 2011-2018 - NIHR Health Technology Assessment Programme “The PRomotion Of Physical activity through structured Education with differing Levels of ongoing Support for those with prediabetes (PROPELS): randomised controlled trial in a diverse multi-ethnic community” (£1.942,284)

       

      • 2012-2017 – NIHR “NIHR Senior Investigator” (£75,000)

       

      • 2004-2014 - Department of Health and Support for Science “ADDITION: A randomised controlled trial of the cost effectiveness of a screening and intensive multifactorial intervention programme for Type 2 Diabetes Mellitus” (£505,000 and £1,674,729 SfS funding)

       

      • 2012-2017 – NIHR BRU “Leicester Diet Nutrition and Lifestyle Biomedical Research Unit” (£4,500,000)

       

      • 2013-2014 – Novo Nordisk “Impact of liraglutide on cardiac function and structure in young adults with type 2 diabetes: an Open-label, Randomised active-comparator” (£106,244)

       

      • 2013-2016 – MRC “Sedentary behaviour in older adults: investigating a new therapeutic paradigm” (£1,055,898)

       

      • 2013-2013 – Novo Nordisk UK Foundation “SWEETBrain Study” (£9872.76)

       

      • 2013-2016 – HTA “Glucose Lowering In Non-diabetic hyperglycaemia Trial (GLINT)” (£668,759)

       

      • 2012-2014 – Primary Care Diabetes Society “Hypoglycaemia Study (Study to Determine the Frequency and Associated Predictors of Hypoglycaemia in People with Type 2 Diabetes Mellitus Managed in Primary Care)” (£220,000)

       

      • 2013-2017 – NIHR “STEPWISE: Structured lifestyle Education for People WIth SchizophrEnia” (£1,757,357)

       

      • 2013-2016 – Department of Health “SMArT Work: Stand More AT Work” (£598,885)

       

      • 2013 – NIHR DRN “Diabetes Research Network Writing Group for Diabetes self-management during fasting/ feasting” (£5000)

       

      • 2014 – The Sir Jules Thorn Charitable Trust “Refurbishment of Lab space” (£98,000)

       

      • 2014-2016 – EU “EU Proposal, “Procurement procedure SANCO/2013/C1/004 concerning a pilot project for developing and implementing successful prevention strategies for type 2 diabetes” (€999,075)

       

      • 2014-2015 - Wellcome Trust Institutional Strategic Fund “A pilot study of the ‘systems biology’ approach in exercise science” (£9,600.00)

       

      • 2014-2019 – NIHR PGfAR “Developing Primary care services for stroke survivors” (£1,999,999)

       

      • 2014-2016 – NIHR “Research methods and fellowships internships” (£84,163)

       

      • 2014-2016 – European Foundation for the study of Diabetes (EFSD) “Process and outcome evaluation of the goal setting component of a type 2 diabetes group self-management programme” (€199,849)