Charlotte Edwardson - Senior Lecturer

       


      Charlotte Edwardson, BSc, MSc, PhD

      Senior Lecturer in Physical Activity, Sedentary Behaviour and Health


      Charlotte Edwards
      • Leicester-Loughborough Diet, Lifestyle and Physical Activity Biomedical Research Unit Affiliate
      • Leicester Clinical Trials Unit Affiliate
      • NIHR CLAHRC East Midlands Affiliate

      Contact Details:

       

      Leicester Diabetes Centre (Air)

      Leicester General Hospital

      Gwendolen Road

      Leicester LE5 4PW, UK

       

      Tel: 0116 258 8577
       
      Email: ce95@le.ac.uk

      Profile:

       

      Charlotte completed a BSc in Applied Sports Science (2004) and MSc (2005) and PhD (part time, 2010) in Physical Activity and Health, all from Loughborough University. Alongside her PhD she worked as a Research Associate (2005-2010) for the Institute of Youth Sport, Loughborough University where she specialised in the evaluation of physical activity and health initiatives in young people. Following this she moved into the area of diabetes prevention and worked as a Research Associate, University Hospitals of Leicester (2010-2013), on several large randomised controlled trials focused on increasing physical activity and reducing sedentary behaviour in people with a high risk of type 2 diabetes.

      In 2013 she was appointed Lecturer, and subsequently Senior Lecturer in 2016, in Physical Activity, Sedentary Behaviour and Health in the Diabetes Research Centre, University of Leicester. Her research focuses on understanding the role of physical activity and sedentary behaviour in the prevention and management of chronic diseases, particularly type 2 diabetes. This encompasses experimental, epidemiological and behaviour change intervention studies. She currently holds research grants (totalling ~£5 million) from the Medical Research Council, National Institute for Health Research, Department of Health and the European Commission.

       


      Research Interests:

       
      • The patterning and profiling of physical activity and sedentary behaviour in different populations
      • The relationship between characteristics of physical activity and sedentary behaviour and health
      • Interventions to increase physical activity and reduce sedentary behaviour
      • Objectively measuring physical activity and sedentary behaviour using the activPAL, ActiGraph and GENEActiv

       

      Current Research Projects:

       

      • Reducing sedentary behaviour in older adults: investigating a new therapeutic Paradigm: Project STAND UP
      • Providing NHS staff with height-adjustable workstations and behaviour change strategies to reduce workplace sitting time: Stand More AT (SMArT) Work cluster randomised controlled trial
      • The impact of cardio-respiratory fitness on an individual’s metabolic response to prolonged sitting and light activity breaks: The Fit 2 Sit study
      • Arming your Health: Investigating whether energy expenditure or posture is the primary driver of an individual’s metabolic response to sedentary behaviour and light activity breaks.
      • Using a novel data capture tool (Autographer) to explore sedentary behaviour, nutrition and associated behaviours in young adults with type 2 diabetes: SNAPSHOT study
      • PROPELS: The promotion of physical activity through structured education with differing levels of ongoing support for those with prediabetes: randomised controlled trial in a diverse multi-ethnic community
      • POST Plus: An obesity related surgery prospective cohort study
      • Prevention strategies for adolescents at risk of type 2 diabetes: A pilot study across 5 European countries (Pre-Start)
      • A cluster randomised controlled trial to investigate the effectiveness and cost effectiveness of the ‘Girls Active’ intervention
      • Stand Out in Class: Restructuring the classroom environment to reduce sedentary behaviour - a pilot cluster randomised controlled trial
      • Development and validation of an automated approach to identify valid waking wear in activPAL data
      • CLASS PAL: Physically active learning in the classroom

       

       

      COMPLETED RESEARCH PROJECTS:

       

      • Project STAND: An intervention to decrease sedentary behaviour in young adults at risk of type 2 diabetes

       

      • Does breaking sedentary time improve glucose regulation in women with impaired glucose tolerance? The ACUTE study

       

      • Walking away from type 2 diabetes: a cluster-randomised controlled trial to investigate the effect of structured education on walking activity in those with a high risk of developing type 2 diabetes

       

       

      Professional Activities:


      Peer reviewer for international journals and conference societies including:

       

      • PLoS ONE
      • International Journal for Behavioural Nutrition and Physical Activity
      • Preventive Medicine
      • Medicine and Science in Sports and Exercise
      • Journal of Physical Activity & Health
      • BMC Public Health
      • Journal of Science and Medicine in Sport
      • BMC Geriatrics
      • Primary Care Diabetes
      • Practical Diabetes
      • Journal of Adolescent Health
      • International Review of Sport and Exercise Psychology
      • International Society for Behavioural Nutrition and Physical Activity

      Associate Editor, BMC Public Health

      Guest Editor, International Congress of Ambulatory Monitoring and Physical Activity Measurement 2015: Focus Issue in Physiological Measurement

      Grant Reviewer, NIHR Public Health Research Programme


      Current Student Supervision:

      Vega Putri, Full Time MSc Student
      Title: Associations of sporadic and prolonged moderate to vigorous physical activity with glucose regulation and insulin sensitivity

      Joanne Paul, BSc placement student, 1 year

      Title: A comparison of sedentary time measured by a modified version of the Adolescent Sedentary Activity Questionnaire and the GENEActiv wrist worn accelerometer

       

      Kishan Bakrania, Full Time PhD Student

      Title: Novel analyses with physical activity and sedentary behaviour data and associations with health

       

      Matthew McCarthy, Full Time PhD student

      Title: Glucose control and metabolic heath in chronic disease: Are novel approaches to increased physical activity/reduced sedentary behaviour effective?

       

      Callum Johnson, Intercalated BSc student

      Title: Physical activity in type 1 diabetes: Using CGM to explore physical activity outcomes

       

      Chia Sadiq, MSc student

      Title: Gestational diabetes and risk of still births: A systematic review


       

      Current Teaching Activities:


       

      MSc Diabetes:

      • Prevention, Screening and Early Detection in Diabetes Module
      • Diabetes and Obesity Module
      • Clinical Presentation and Management of Diabetes Module

       

      PUBLICATIONS:

      1.  Rowlands AV, Yates T, Davies MJ, Khunti K, Edwardson CL. (2016). Raw accelerometer data analysis with GGIR R-package: Does accelerometer brand matter? Medicine and Science in Sports and Exercise. May 13. [Epub ahead of print].
      2. Sanders J, Loveday A, Pearson NL, Edwardson CL, Yates T, Esliger D. (2016). Devices for self-monitoring sedentary time and/or physical activity: A systematic review. Journal of Medical Internet Research. 18(5):e90.
      3. Bakrania K, Edwardson CL. Bodicoat DH, Esliger DW, Gill JM, Kazi A, Velayudhan L, Sinclair AJ, Sattar N, Biddle SJ, Khunti K, Davies MJ. (2016). Associations of mutually exclusive categories of physical activity and sedentary behaviour with markers of health in English adults: cross sectional analysis of the Health Survey for England. BMC Public Health. 16:25.
      4. Edwardson CL, Rowlands AV, Bunnewell S, Sanders J, Esliger D, Gorely T, O’Connell, Davies MJ, Khunti K, Yates T. (2016). Accuracy of posture allocation algorithms for thigh and waist-worn accelerometers. Medicine and Science in Sports and Exercise. 48:1085-90.
      5. Edwardson C, Bodicoat, D, Winkler E, Yates T, Dunstan D, Healy G (2016). Considerations when using the activPAL monitor in field based research with adult populations. Journal of Sport and Health Science. In Press.
      6. O’Connell S, Edwardson CL, Jackson B, Yates T, Davies MJ, Gray LJ, Bidlde SJH, Esliger D, Dunstan D, Munir F. (2015). Providing NHS staff with height-adjustable desks and behaviour change strategies to reduce sitting time: Protocol for the SMArT Work cluster randomised controlled trial. BMC Public Health. 15(1):1219.
      7. Biddle, S, Edwardson C, Wilmot E, Yates T, Gorely T, Bodicoat D, Khunti K, Nimmo M, Davies M. (2015). A randomised controlled trial to reduce sedentary time in adults at risk of Type 2 Diabetes Mellitus: Project STAND (Sedentary Time and Diabetes). PLoS ONE. 10(12):e0143398.
      8. Rowlands A.V, Yates T, Olds T.S, Davies D, Khunti K, Edwardson C.L. (2016)  Sedentary Sphere: Monitor-brand independent posture classification from wrist accelerometry. Medicine and Science in Sports and Exercise. 48:748-54.
      9. Henson J, Davies M.J, Bodicoat D.H, Edwardson C.L, Gill J, Stensel D, Tolfrey K, Dunstan D, Khunti K, Yates T. (2016)  Breaking up prolonged sitting with standing or light activity reduces post-prandial markers of diabetes risk. Diabetes Care. 39:130-38.
      10. Yates T, Griffin S, Bodicoat D, Brierly G, Dallosso H, Davies MJ, Eborall H, Edwardson C, Gillett M, Gray LJ, Hardeman W, Hill S, Morton K, Sutton S, Troughton J, and Khunti K (2015). PRomotion Of Physical activity through structured Education with differing Levels of ongoing Support for people at high risk  of type 2 diabetes (PROPELS): study protocol for a randomised controlled trial. Trials. 16, 289.  
      11. Edwardson C, Harrington D, Yates T, Bodicoat D, Khunti K, Gorely T, Sherar L, Tudor-Edwards R, Davies M. (2015). A cluster randomized controlled trial to investigate the effectiveness and cost effectiveness of the ‘Girls Active’ intervention: a study protocol. BMC Public Health. 15:526  doi:10.1186/s12889-015-1886-z.
      12. Mansoubi M, Pearson N, Clemes SA, Biddle SJH, Bodicoat DH, Tolfrey K,Edwardson CL, Yates T. (2015). Energy expenditure during common sitting, standing and walking tasks: examining the 1.5 MET definition of sedentary behaviour. BMC Public Health, 15:516  doi:10.1186/s12889-015-1851-x.
      13. Yates T, Henson J, Edwardson C, Dunstan D, Bodicoat D, Khunti K, Davies M. (2015). Objectively measured sedentary time and associations with insulin sensitivity: Importance of re-allocating sedentary time to physical activity. Preventive Medicine. 76:79-83. 
      14. Yates T, Davies MJ, Henson J, Edwardson C, Webb D, Bodicoat DH, Webb B, Howard P, Cooper J, Humphries S, Khunti K, Talmud P. (2015). Effect of the PPARG2 Pro12Ala polymorphism on associations of physical activity and sedentary behaviour with markers of insulin sensitivity in those with an elevated risk of type 2 diabetes. PLoS ONE. 10(5):e0124062.
      15. Yates T, Henson J, Edwardson C, Bodicoat DH, Davies MJ, Khunti K. (2015). Differences in levels of physical activity between white and black and minority ethnic populations within a health care setting: Impact of measurement type in a cross-sectional study. BMJ Open. 5(7):e006181
      16. Henson J, Edwardson C, Morgan B, Horsfield M, Bodicoat D, Biddle S, Gorely T, Nimmo M, McCann G, Khunti K, Davies M, and Yates T. (2014). Associations of sedentary time with regional fat distribution in a population at high risk of type 2 diabetes. Medicine and Science in Sports and Exercise. [Epub ahead of print].
      17. Bodicoat DH, O’Donovan G, Dalton AM, Edwardson C, Gray LJ, Hill S, Webb D, Yates T, Khunti K, Davies MJ, Jones AP. (2014). The association between neighbourhood greenspace and type 2 diabetes in a large cross-sectional study. BMJ Open. 4(12): e006076.
      18. Bodicoat DH, Carter P, Comber AJ, Edwardson C, Gray LJ, Hill SA, Webb D, Yates TE, Davies MJ, Khunti K. (2014). Is the number of fast food outlets in the neighbourhood related to screen-detected type 2 diabetes mellitus and associated risk factors? A cross-sectional analysis. Public Health Nutrition. 1-8. [Epub ahead of print].
      19. Edwardson C, Gray LJ, Yates T, Barber SR, Khunti K, Davies MJ. Detection and early lifestyle intervention in those at risk of type 2 diabetes. European Medical Journal. 2:48-57.
      20. Yates T, Davies M, Edwardson C, Morris D, Biddle SJH, Khunti K. (In Press). Adverse metabolic responses and physical activity: analysis of the PREPARE trial. 46(8):1617-1623. 
      21. Clemes S, O Connell S, Edwardson C. (In Press). Office workers objectively measured sedentary behaviour and physical activity during and outside working hours. Journal of Occupational and Environmental Medicine.
      22. Henson J, Yates T, Edwardson C, Khunti K, Talbot D, Gray L, Leigh T, Carter P, Davies M. Sedentary time and markers of chronic low-grade inflammation in a high risk population. PLoS ONE. 8 (10):e78350.
      23. Henson J, Yates T, Biddle SJH, Edwardson C, Khunti K, Wilmot E, Gray L, Gorely T, Nimmo M, Davies M. (2013). Associations of objectively measured sedentary behaviour and physical activity with markers of cardio-metabolic health. Diabetologia. 56(5):1012-1020.
      24. Yates T, Henson J, Khunti K, Morris D, Edwardson C, Brady E, Davies M. (2013). Effect of physical activity measurement type on the association between walking activity and glucose regulation in a high risk population recruited from primary care. International Journal of Epidemiology. 42(2):533-540.
      25. Wilmot E, Edwardson C, Biddle SJH, Gorely T, Henson J, Khunti K, Yates T, Davies M. (2013). Prevalence of diabetes and impaired glucose metabolism in younger ‘at risk’ UK adults: insights from the STAND programme of research. Diabet Med. 30(6):671-675.
      26. Edwardson C, Gorely T, Pearson N, Atkin A. (2013). Sources of activity-related social support and adolescents’ objectively measured after school and weekend physical activity: Gender and age differences. J Phys Act Health. 10(8):1153-8.
      27. Edwardson C, Gorely T, Musson H, Duncombe R, Sandford, R. (2014). Does activity-related social support differ by characteristics of the adolescent. J Phys Act Health. 11(3):574-80.
      28. Gray L, Khunti K, Edwardson C, Goldby S, Henson J, Morris D, Sheppard D, Williams S, Yates T, Davies M. (2012). Implementation of the Leicester Diabetes Risk Score in two diabetes prevention trials. Diabetologia. 55(12): 3238-3244.
      29. Wilmot EG, Edwardson C, Davies MJ, Gorely T, Gray L, Khunti K, Yates T, Biddle S. (2012). Sitting time in adults and the association with diabetes, cardiovascular disease and death: systematic review and meta-analysis. Diabetologia. 55(11): 2895-2905.
      30. Atkin AJ, Gorely T, Clemes SA, Yates T, Edwardson C, Brage S, Salmon J, Marshall SJ, Biddle SJH. (2012). Methods of measuring sedentary behaviour in epidemiological research. Int J  Epidemiol. 41 (5):1460-1471.
      31. Edwardson C, Gorely T, Davies MJ, Gray L, Khunti K, Wilmot EG, Yates T, Biddle S. (2012). Association of sedentary behaviour with metabolic syndrome: A meta-analysis. PLoS ONE 7 (4): e34916. doi:10.1371/journal.pone.0034916.
      32. Yates T, Davies MJ, Henson J, Troughton J, Edwardson C, Gray LJ, Khunti K. (2012) Walking away from type 2 diabetes: trial protocol of a cluster randomized controlled trial evaluating a structured education programme in those at high risk of developing type 2 diabetes. BMC Fam Pract, 13:46.
      33. Bharakhada N, Yates T, Davies MJ, Wilmot EG, Edwardson C, Henson J, Webb W, Khunti K. (2012). Association of sitting time and physical activity with CKD: A cross-sectional study in family practices. Am J Kidney Dis, 60(4):583-90.
      34. Wilmot EG, Davies MJ, Edwardson C, Gorely T, Khunti K, Nimmo M, Yates T, Biddle SJH. (2011). Rationale and Study Design for a Randomised Controlled Trial to Reduce Sedentary Time in Adults at Risk of Type 2 Diabetes Mellitus: Project STAND (Sedentary Time ANd Diabetes). BMC Public Health, 11, 908
      35. Yates T, Wilmot EG, Davies MJ, Gorely T, Edwardson C, Biddle S. Khunti K. (2011). Sedentary behaviour what’s in a definition. American Journal of Preventive Medicine, 40 (6), e33-4.
      36. Edwardson C, Gorely T. (2010). Parental Influences on Different Types and Intensities of Physical Activity in Youth: A Systematic Review. Psychology of Sport and Exercise, 11 (6), 522-535.
      37. Edwardson C, Gorely T. (2010). Epoch length and its effect on physical activity intensity. Med Sci Sports Exerc. 42 (5), 928-934.
      38. Edwardson C, Gorely T. (2010). Activity-related parenting practices and children’s objectively measured physical activity. Pediatr Exerc Sci, 22, 105-113.
      39. Pearson N, Atkin AJ, Biddle SJH, Gorely T, Edwardson C. (2009) Patterns of adolescent physical activity and dietary behaviours. Int J Behav Nutr Phys Act, 6, 45.
      40. Pearson N, Atkin AJ, Biddle SJH, Gorely T, Edwardson C. (2009). Parenting styles, family structure and adolescent dietary behaviour. Public Health Nutr, 3, 1-9.

      Current Grants Held:

      Title: The use of a novel data capture tool to gain a detailed understanding of sedentary behaviour in young adults with type 2 diabetes.

      Funding Body: Wellcome Trust Institutional Strategic Support Fund

      Grant Holder: Dr Charlotte Edwardson (University of Leicester)

      Award : £6733

      Duration : May 2014-May 2015


      Title: Sedentary behaviour in older adults: Investigating a new therapeutic paradigm

      Funding Body: Medical Research CouncilGrant Holder: Dr Thomas Yates (University of Leicester)

      Award: £1,055,898

      Duration: November 2013-November 2016

       

      Title:SMArT Work: Stand More AT Work

      Funding Body: Department of HealthGrant Holder: Professor Stuart Biddle (Loughborough University)Award: £598,885

      Duration: March 2014-March 2017


      Title: A pilot project for developing and implementing successful prevention strategies for type 2 diabetes in adolescents

      Funding Body: European CommissionGrant Holder: Professor Melanie Davies (University of Leicester)

      Award: 999,075 Euros

      Duration: June 2014 – June 2016


      Title: A cluster randomised controlled trial to investigate the effectiveness and cost-effectiveness of the ‘Girls Active’ intervention

      Funding Body:NIHR PHR

      Grant Holder: Professor Melanie Davies (University of Leicester)

      Award:£599,444

      Duration: February 2015-February 2017

       

      Title: ‘Move to Teach, Move to Learn’ - A collaborative school based

      programme to decrease sedentary time in primary school students

      Funding Body: East Midlands CLAHRC

      Grant Holder: Dr Lauren Sherar (Loughborough University)

      Award:£253,468

      Duration: July 2014-February 2018

      Title: Promoting lifestyle change and self-management through structured education in people with multi-morbidity: A randomised controlled trial

      Funding Body: East Midlands CLAHRC

      Grant Holder: Professor Kamlesh Khunti (University of Leicester)

      Award:£248,858

      Duration: 2015-2018

       

       

      Title: SGLT-2 Inhibitor Empagliflozin Effects on Appetite and Weight Regulation – The SEESAW Study

      Funding Body: Boehringer Ingelheim

      Grant Holder: Professor Melanie Davies (University of Leicester)

      Award: 497,002 Euros

      Duration: 2015-2017

       
      Title: Stand Out in Class: Restructuring the classroom environment to reduce sedentary behaviour - a pilot cluster randomised controlled trial
      Funding Body: NIHR PHR Grant Holder: Dr Stacy Clemes (Loughborough University)
      Award: £418,112
      Duration: 2016-2017

       

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