Balu Webb - Research Scientist


      M’Balu Webb, BSc, M Med Sci, PhD
      Research Scientist , Leicester Diabetes Centre


      Balu Webb- Research Scientist

      Research Interests:

      • Beta cell neogenesis
      • Nutritional status and diabetes
      • Novel biomarkers of insulin resistance and diabetes
       

      Research Projects:

      Biomarker analysis of biological samples for the following studies:

      • The SWEETHeart Study- Early detection of impaired glucose regulation post myocardial infarction.
      • The SUCCESS Study - StructUred eduCation programme to improve Cardiovascular risk in womEn with polycyStic ovary Syndrome.
      • The TRIMS Study - The Reversal Intervention for Metabolic Syndrome

       

      Current Teaching Activities:

       

      Laboratory supervision of one PhD and one intercalated BSc student

       

      Contact Details:

       

      Leicester Diabetes Centre (Broadleaf)

      Leicester General Hospital

      Gwendolen Road

      Leicester LE5 4PW, UK

       

      Tel: 0116 258 9831 

       

      Fax: 0116 258 8405

       

      email: balu.webb@uhl-tr.nhs.uk



      PUBLICATIONS:

       

      1. Hall T, Garcea G, Webb M; Al-leswas D, Metcalfe M, Dennison A. The socioeconomic impact of chronic pancreatitis: A systematic review. Journal of Evaluation in Clinical Practice 2014; In Press.

      2. Garcea G, Pollard CA, Illouz S, Webb M, Metcalfe MS, Dennison AR. Patient satisfaction and cost-effectiveness following total pancreatectomy with islet cell transplantation for chronic pancreatitis. Pancreas 2013 Mar;42(2):322-328.

      3. Webb MA, Chen JJ, Illouz SC, Pollard CA, Dennison B, West KP, et al. The impact of potential islet precursor cells on islet autotransplantation outcomes. Cell Transplant 2013;22(6):1041-1051.

      4. Webb MA, Dennison AR, James RF. The potential benefit of non-purified islets preparations for islet transplantation. Biotechnol Genet Eng Rev 2012;28:101-114.

      5. Pollard C, Gravante G, Webb M, Chung WY, Illouz S, Ong SL, et al. Use of the Recanalised Umbilical Vein for Islet Autotransplantation following Total Pancreatectomy. Pancreatology 2011 May 17;11(2):233-239.

      6. Ong SL, Gravante G, Pollard CA, Webb MA, Illouz S, Dennison AR. Total pancreatectomy with islet autotransplantation: an overview. HPB (Oxford) 2009 Dec;11(8):613-621.

      7. Spencer L, Mann C, Metcalfe M, Webb M, Pollard C, Spencer D, et al. The effect of omega-3 FAs on tumour angiogenesis and their therapeutic potential. Eur J Cancer 2009 Aug;45(12):2077-2086.

      8. Garcea G, Weaver J, Phillips J, Pollard CA, Ilouz SC, Webb MA, et al. Total Pancreatectomy With and Without Islet Cell Transplantation for Chronic Pancreatitis: A Series of 85 Consecutive Patients. Pancreas 2008 Jul 24.

      9. Illouz S, Alexandre E, Pattenden C, Mark L, Bachellier P, Webb M, et al. Differential effects of curcumin on cryopreserved versus fresh primary human hepatocytes. Phytother Res 2008 Aug 11.

      10.  Ong SL, Pollard C, Rees Y, Garcea G, Webb M, Illouz S, et al. Ultrasound changes within the liver after total pancreatectomy and intrahepatic islet cell autotransplantation. Transplantation 2008 Jun 27;85(12):1773-1777.

      11. Illouz S, Nakamura T, Webb M, Thava B, Bikchandani J, Robertson G, et al. Comparison of University of Wisconsin and ET-Kyoto preservation solutions for the cryopreservation of primary human hepatocytes. Transplant Proc 2008 Jun;40(5):1706-1709.

      12. Webb MA, Illouz SC, Pollard CA, Gregory R, Mayberry JF, Tordoff SG, et al. Islet auto transplantation following total pancreatectomy: a long-term assessment of graft function. Pancreas 2008 Oct;37(3):282-287.

      13. Illouz S, Webb M, Pollard C, Musto P, O'Reilly K, Berry D, et al. Islet autotransplantation restores normal glucose tolerance in a patient with chronic pancreatitis. Diabetes Care 2007 Dec;30(12):e130.

      14. Webb MA, Platton SL, Dennison AR, James RF. Immunohistochemical evidence that culture in the high aspect rotating vessel can up-regulate hormone expression in growth dedifferentiated PHHI-derived islet cells. In Vitro Cell Dev Biol Anim 2007 Jul-Aug;43(7):210-214.

      15. Webb MA(15) , Illouz SC, Pollard CA, Musto PP, Berry D, Dennison AR. Long-term maintenance of graft function after islet autotransplantation of less than 1000 IEQ/kg. Pancreas 2006 Nov;33(4):433-434.

      16. Webb M, James RF. Growth restriction and exendin 4 promote endocrine expression in cultured islet cells derived from patients with persistent hyperinsulinemic hypoglycemia of infancy (PHHI). Endocr Res 2005;31(2):99-109.

      17. Walker RA, Lees E, Webb MB, Dearing SJ. Breast carcinomas occurring in young women (< 35 years) are different. Br J Cancer 1996 Dec;74(11):1796-1800.

         

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